Disease

Gigantism

Gigantism is a disease that is accompanied by increased production growth hormone in the anterior pituitary gland (adenohypophysis), which leads to excessive growth of the limbs and the entire body. Symptoms of gigantism are most often manifested in boys aged 7-10 years, or during puberty, and develops throughout the entire growth period. The growth indicators of the child exceed the norms of this gender and age, and by the end of puberty can reach 2 m in men and 1.90 m in women, while maintaining a proportionate physique. The frequency of manifestations of gigantism is 1-3 people per 1000 population. Gigantism is usually accompanied by fatigue and headaches, gradual memory impairment and sexual dysfunction. With gigantism, concomitant can also be observed endocrine disorders, namely: diabetes, hypo or hyperthyroidismdisorders of carbohydrate metabolism.

The basis of gigantism is increased production of the pituitary gland growth hormone, the reasons for which are: hereditary predisposition, tumors of the adenohypophysis (pituitary adenoma), infectious diseases of the central nervous system (meningitis, encephalitis, abscess), head injuries and poisoning by toxins. Another cause of the disease of gigantism may be a decrease in the sensitivity of the receptors of the cartilage tissue, where the growth zone of the bone is located, to sex hormones, as a result of which the zone remains open, i.e. capable of further growth and after the end of puberty.

Symptoms of Gigantism

The main symptoms of gigantism are the patient's complaints about high growthexcessive growth rate, pain in joints and bones, muscle weakness, decreased performance in school, often - to a decrease in vision (myopia, farsightedness, astigmatism) Disorders in the thyroid and pancreas can also be observed.

The diagnosis of gigantism

To make a diagnosis of gigantism, the endocrinologist examines the patient, prescribes a study of X-ray of the skull, and computed and magnetic resonance imaging of the brain, which can be used to identify tumors in the pituitary gland. With a growing tumor in patients, vision often worsens, so an ophthalmic examination can also be prescribed, which will reveal visual field limitations and congestion in the fundus. Diagnosis of gigantism also includes laboratory blood tests. A blood test result will show an increased level concentration growth hormone.

The treatment of gigantism

Used to treat gigantism conservative and surgical treatment methods. To normalize the level of growth hormone in the body and accelerate the closure of bone growth zones, patients with gigantism are prescribed hormone therapy consisting of a course somatostatin and sex hormones. Surgical treatment methods include radiation therapy to remove the pituitary adenoma, or its surgical removal, in combination with medical support dopamine agonists (parlodel, dostinex) A complex treatment of gigantism is currently being used, which combines radiation and hormonal therapy, which allows for significant improvement in a large number of patients with gigantism.

The doctors

specialization: Endocrinologist

Ermekova Batima Kusainovna

10 reviews1500 rub.

Konovalova Anna Borisovna

3 reviews1800 rub.

Kuznetsova Elena Yuryevna

4 reviews 1,240 rubles more doctors

Medication

SomatostatinBromocriptineParlodelOctreotideSomatulinSandostatin

Gigantism Prevention

The basis for the prevention of gigantism is the fight against epidemic diseasesthat can disrupt the growth process. It is also important to avoid excessive intake of vitamins and timely treat peripheral endocrine disorders in children, especially sexual infantilism. As the prevention of gigantism, scheduled examinations of young men aged 13-16 are carried out to identify signs of gigantism. Timely detection of the first symptoms of gigantism can contribute to its complete cure.

List of sources

  • Clinical endocrinology. Leadership / N. T. Starkova. - 3rd edition, revised and supplemented. - St. Petersburg: Peter, 2002 .-- S. 46-62. - 576 p.
  • Endocrinology / ed. N. Avalanche. - M.: Medicine, 2009 .-- 832 p.
  • Acromegaly and gigantism: A. S. Ametov, E. V. Doskina - St. Petersburg, GEOTAR-Media, 2010 - 156 p.

Watch the video: DOCS: Turning Into A Giant (January 2020).

Popular Posts

Category Disease, Next Article

Diet and proper nutrition for athletes
Diets

Diet and proper nutrition for athletes

General rules At the heart of modern sport, regardless of its type, are intense physical activity and high neuro-emotional stress. To achieve high sports results, along with the training process, the leading place is given to the athlete's proper nutrition.This is the basis of intense physical performance and recovery of energy costs of the athlete's body during the rest period.
Read More
Baby Food Diet
Diets

Baby Food Diet

General rules In the world practice of dietetics and methods of painless weight loss, a diet has become a real discovery, the diet of which consists exclusively of canned baby food. The bright female representatives who successfully lost weight in this way are the pop divas Beyonce and Lady Gaga, actresses Reese Witherspoon and Jennifer Aniston.
Read More
Milk and Vegetable Diet
Diets

Milk and Vegetable Diet

General rules As the name implies, the dairy and vegetable diet is based on the inclusion in the diet of dairy products and vegetable products of vegetables and fruits. At the same time, the choice of dairy and vegetable products is wide enough, which determines certain diet options. From dairy products, you can use low-fat cow's milk, cottage cheese, natural yogurt, kefir, fermented baked milk.
Read More
Ryazhenka diet
Diets

Ryazhenka diet

General rules Many people prefer the use of fermented baked milk kefir, as it is tender and pleasant to taste, sweeter and more satisfying. This is a fermented milk product of natural origin, made from baked milk, fermented with pure cultures of lactic acid bacteria. The product does not contain artificial ingredients.
Read More