Medication

Aspirin

Aspirin Composition

The composition of the tablets includes 500 mg acetylsalicylic acid (ASA), as well as corn starch and microcrystalline cellulose.

Release form

The form of the drug is tablets.

Pharmachologic effect

The drug relieves inflammation and pain, and also acts as antipyretic and disaggregant.

Pharmacological group: NSAIDs - derivatives salicylic acid.

Pharmacodynamics and pharmacokinetics

What is aspirin?

The active substance of the drug is acetylsalicylic acid (sometimes it is erroneously called “acetyl acid”) - refers to the group non-steroidal anti-inflammatory drugswhose mechanism of action is realized due to the irreversible inactivation of the COX enzyme, which plays an important role in the synthesis of thromboxanes and Pg.

So the question is acetylsalicylic acid - is it aspirin or not, it is safe to answer that Aspirin and acetylsalicylic acid - same .

Natural source of Aspirin: bark Salix alba (white willow).

The chemical formula of Aspirin: C₉H₈O₄.

Pharmacodynamics

Oral administration of ASA in a dose of 300 mg to 1 g helps to alleviate pain (including muscle and joint) and conditions accompanied by mild fever (for example, with a cold or flu). Similar doses of ASA are prescribed by temperature.

The properties of ASA allow the use of the drug also with acute and chronic inflammatory diseases. In the list of indications from which Aspirin helps, are listed osteoarthritis, rheumatoid arthritis, Ankylosing spondylitis.

In these diseases, as a rule, higher doses are used than, for example, at a temperature or with a cold. To alleviate the condition, an adult, depending on the characteristics of the course of the disease, is prescribed from 4 to 8 g of ASA per day.

By blocking the synthesis of thromboxane A2, ASA inhibits aggregation platelet count. This makes it advisable to use it with a large number of vascular diseases. The daily dose for such pathologies varies from 75 to 300 mg.

Pharmacokinetics

After taking the Aspirin tablet, ASA is rapidly and completely absorbed from the digestive tract. During and after absorption, it is biotransformed into salicylic acid (SC) - the main, pharmacologically active metabolite.

TSmakh ASA - 10-20 minutes, salicylates - from 20 minutes to 2 hours. ASA and SC are fully linked in blood with plasma proteins and are rapidly distributed in the body. SC passes through the placenta and passes into breast milk.

AT metabolism SC involved the liver. The products of the metabolism of the substance are: gentisic, gentisin uric, salicylic uric acid, as well as salicylacyl and salicylphenol glucuronides.

The kinetics of SC excretion is dose-dependent, since metabolism is limited by hepatic activity enzymes. T1 / 2 is also a dose-dependent value: in the case of applying low doses of T1 / 2 - from 2 to 3 hours, in the case of applying high doses - increases to 15 hours.

SC and products of its metabolism are excreted mainly by the kidneys.

Indications for use Aspirin

Aspirin (ASA) is a symptomatic remedy used in conditions involving pain, inflammation, and fever.

Indications for use:

  • headache;
  • toothache;
  • algodismenorea;
  • sore throat caused by a cold;
  • muscle and joint pain;
  • backache;
  • ARVI and a cold;
  • moderate pain with joint inflammation.

Contraindications for Aspirin

Contraindications are divided into absolute and relative.

Taking the drug is strictly prohibited with allergies on ASK or any other non-steroidal anti-inflammatory drugs (Analgin, Paracetamol etc.), as well as in conditions that are characterized by an increased tendency to bleeding.

The following contraindications are relative:

  • simultaneous reception anticoagulants;
  • deficiency of the cytosolic enzyme G6PD;
  • bronchial asthma;
  • impaired renal function;
  • chronic diseases of the stomach and duodenum;
  • diabetes;
  • gout;
  • children under 12 years old;
  • pregnancy;
  • lactation.

In the presence of relative contraindications Aspirin Bayer can only be taken after the doctor approves it.

Side effects

Side effects:

  • hypersensitivity reactions (skin rashes, bronchospasm);
  • level reduction platelet count in blood;
  • pain in the stomach.

Frequent and prolonged use of ASA in some cases may be accompanied by the development of bleeding from the gastrointestinal tract, the signs of which are:

  • tarry stool;
  • anemia;
  • general weakness;
  • persistent abdominal pain.

The appearance of such symptoms requires the discontinuation of Aspirin and immediate medical attention.

Long-term treatment with high doses of ASA can also provoke:

  • damage to the juxtaglomerular apparatus (peri-buccal complex) of the kidneys;
  • the formation of oxalate and / or urate stones in the urinary tract and kidneys;
  • renal failure;
  • damage to the pancreatic insular apparatus;
  • impaired glycogen synthesis (in some cases up to development diabetes mellitus);
  • thrombocytosis;
  • myocardial dystrophy;
  • hemolytic anemia, erythrocytopenia, hyperprothrombinemia, neutrophilic leukocytosis;
  • decrease in capillary permeability (increase is possible HELL and deterioration of tissue trophism);
  • hemolysis red blood cells (in patients with G6PD deficiency);
  • impaired metabolism of copper and zinc;
  • dysbiosis of the oral cavity.

Aspirin tablets, instructions for use

The instructions for use of Aspirin indicate that tablets should be taken orally after a meal with a sufficient amount of liquid.

The maximum duration of drug treatment without medical advice is 5 days.

As a single dose, adults are prescribed from 300 mg to 1 g of ASA. Repeated reception is possible after 4-8 hours. The permissible upper limit of the daily dose is 4 g.

Aspirin: how to drink to prevent heart and vascular disease?

A systematic review of various studies showed that the use of Aspirin after myocardial infarction reduces the frequency by 31% non-fatal heart attacks, 39% - frequency non-fatal strokes, 25% - frequency recurrent strokes and heart attacks, as well as 15% - vascular death.

Moreover, the positive effect of ASA does not depend on gender, age, or availability diabetes mellitus and indicators blood pressure.

In the course of research it was found that after myocardial infarction ASA should be prescribed immediately, and treatment should continue until specific contraindications are identified. The optimal dosage for vascular prophylaxis is 160-325 mg / day.

How to drink Aspirin?

It is recommended to drink Aspirin tablets with milk, jelly or sodium bicarbonate mineral water.

Aspirin for blood thinning: does blood thinning ASA?

ASK is disaggregant. This property of the drug allows its use in conditions when it is necessary to create obstacles to induced or spontaneous aggregation platelet count.

There are 2 groups of blood-thinning drugs: without ASA and based on this substance. Blood thinners without ASA are anticoagulants. Medicines based on ASA belong to the group antiplatelet agents.

When asked whether or not Aspirin dilutes the blood, doctors answer that the meaning of exposure disaggregants (and, in particular, ASA) is that they lower the ability platelet count stick together, which in turn reduces the risk of formation blood clots.

What is aspirin for? The following recommendations are given in the instructions and on Wikipedia: the drug should be prescribed to patients with high cardiovascular risk, people who have undergone myocardial infarctionas well as in the acute period ischemic stroke, with circulatory disorders in the brain and other manifestations atherosclerosis.

Elena Malysheva about the drug says the following: “The cure for old age. There are no blood clots in the vessels, good blood flow in the brain, in the heart, in the legs, in the hands. In the skin!" She also notes that the tool reduces the risk atherosclerosis and protects the body from cancer.

The tips on how to take Aspirin to thin the blood correctly are as follows: the optimal dose of the drug if used to prevent vascular complications is a dose of 75-100 mg / day. It is this dose that is considered the most well-balanced in terms of safety / efficacy.

Western doctors do not practice the use of Aspirin for blood thinning, however, in Russia it is recommended for these purposes quite often. Knowing the benefits of ASA for blood vessels, some people begin to take the drug uncontrollably.

Doctors do not tire of reminding that before drinking Aspirin to cleanse the vascular walls of cholesterol and “softening” the blood, it is necessary to obtain the approval of a doctor.

What is harmful Aspirin? Studies conducted by scientists in the 70s of the XX century showed that ASA drugs affect blood viscosity, thereby helping to reduce the load on the heart muscle and preventing the increase in blood pressure.

However, 50-75 mg of the substance per day is usually sufficient to achieve these effects. Regular excess of the recommended preventive dose can give directly opposite results and harm the body.

In other words, taking ASA to thin the blood, if there are no signs of heart disease, affects the body negatively.

How to replace ASK?

Often, patients wonder what dilutes blood other than Aspirin. As an alternative to drugs, you can use individual blood thinning products - analogues antiplatelet agents.

The main ones are those that contain salicylic acid, vitamin e and iodine. Herbal substitutes for Aspirin are licorice, sage, aloe, horse chestnut. Also, to thin the blood, it is good to introduce cherries, oranges, cranberries, raisins, grapes, tangerines, blueberries, thyme, mint into the diet ginger and curry.

Meat, fish and dairy products do not contribute to blood thinning, but regular consumption of fish helps to improve the blood picture. Blood becomes less viscous even when the body receives enough vitamin D.

It is recommended that pregnant women thin the blood with eggplant, zucchini, cabbage, onions, horseradish, capsicum, lemons, pomegranates, currants, cranberries, viburnum.

Does Aspirin lower or increase blood pressure? Aspirin for headache

Aspirin from headache particularly effective if the cause of pain is increased intracranial pressure (ICP). This is due to the fact that ASA has a hemorrhaging effect and thus helps to reduce ICP.

Adults with a headache (depending on its intensity) are usually prescribed to take from 0.25 to 1 g of ASA every 6-8 hours.

How to take for the prevention of aspirin for varicose veins?

The action of ASA is aimed at suppressing function platelet count. As a result, when varicose veins regular use of the drug reduces risk thrombosis.

However, doctors question “Can I drink Aspirin every day?”They say that abuse this drug with varicose veins still not worth it. The optimal way to use the product is special medical compresses.

To prepare a compress, it is recommended to pour 200 ml of alcohol (vodka) ground Aspirin tablets (10 pieces) and insist on the medicine for 48 hours. Compresses are applied to the area of ​​dilated veins daily, at night. Such a procedure for varicose veins Helps eliminate pain.

What is Aspirin useful in cosmetology?

In cosmetology, ASA is used for hair (in particular, as a remedy for dandruff), for the treatment of acne and skin improvement. The effectiveness of the drug is confirmed by a large number of positive reviews and pictures, on which you can evaluate the appearance of the face before and after applying Aspirin.

For face skin, ASA is used as part of creams for daily care, as well as in masks. The benefit of this treatment for the face is that quickly and within a few hours, inflammation and redness disappear from the skin and tissue swelling subsides.

In addition, face masks with Aspirin help exfoliate a layer of dead cells and cleanse pores from subcutaneous fat.

To the question of how it helps from acne on the face Aspirin, cosmetologists say that the ability to clean pores is due to the drying effect and good solubility in fats, due to which ASA can penetrate deep enough into pores clogged with sebum.

Easy peeling is guaranteed due to the granular structure of the dissolved preparation. In this case, the product does not injure healthy areas of the skin. This is due to the fact that ASA works somewhat differently than abrasive scrubs whose exfoliating effect is realized due to the presence of coarse particles in their composition.

The action of ASA, in contrast to such agents, is aimed at weakening the adhesive bonds between cells, which in turn helps to remove dead cells from the skin surface without damaging young healthy cells in the deeper layers.

The easiest recipe for acne is to put half the tablet of the drug on the inflamed area.

You can also add crushed Aspirin tablets to the cream. To prepare the composition, 4 tablets of the drug are placed in a bowl and dripped on them with water. When the medicine begins to dissolve, it is rubbed with your fingers to a mushy consistency and then mixed with a trowel with 2 tbsp. tablespoons of cream.

To acne remedy had a finer texture, up to 1 tbsp can be added to the mixture. tablespoons of warm water. The cream is applied to the face, and after 15 minutes, washed off with warm water.

Acne aspirin can also be used in combination with freshly squeezed lemon juice.

The recipe for such a mask from Aspirin against acne is simple: 6 tablets of the drug are ground with lemon and juice until a homogeneous mass is obtained (reviews suggest that the process of dissolving the tablets can stretch for 10 minutes), and then the resulting paste is applied pointwise to acne and left to dry.

It is recommended to remove the paste from the skin to neutralize the acid with a solution of baking soda.

Good reviews about the face mask with Aspirin and honey. To prepare the medicinal composition, 3 tablets should be placed in a bowl (not used effervescent Aspirin UPSA, and ordinary tablets) and drip on them with water. When the tablets become loose, add 0.5-1 teaspoon of honey to them and mix thoroughly.

If the honey is too thick, you can add a few drops of water to the mixture. The mask is applied to dry skin for 15 minutes, and then gently wash the face with warm water in a circular motion.

The mask of honey and Aspirin is most suitable for aging, oily and porous skin, but cosmetologists say that you can use such a mask with honey and acne.

A good acne mask with Aspirin and clay. To prepare it, you need to take 6 tablets of ASA, 2 teaspoons of cosmetic clay (blue or white) and a small amount of warm water.

All ingredients are stirred in a convenient container until gruel is obtained, after which the composition is applied for 15 minutes using a cotton pad to the face. If you experience unpleasant sensations (burning, itching), the mask can be washed off earlier. After the procedure, it is recommended to wipe the skin with a sponge dipped in chamomile broth or a string.

To eliminate small acne and black spots, Aspirin is used in combination with sparkling mineral water and black cosmetic clay. On 1 tbsp. a spoonful of clay you need to take 1 tablet of ASA.First, clay is diluted with mineral water, then Aspirin is added to the resulting slurry.

The composition is applied to the skin with a thin layer. The exposure time is 20 minutes. It is recommended to apply the cream after the procedure no earlier than after 10-15 minutes (this will allow the skin to “breathe”).

Effective against acne Chloramphenicol, calendula and Aspirin in the form of a talker. To prepare the product, add 4 tablets of each drug to 40 ml of calendula tincture and shake the bottle well. The solution is used to wipe the face.

Face cleaning with Aspirin is carried out using only tablets in a pure form. It should be remembered that there are different types of ASAs on sale. However, for peeling, tablets without additional coating should be used; Aspirin in the shell is not used for these purposes.

A soaked tablet of the drug is placed on a cotton pad, and then applied in circular movements to the face for 3 minutes and then washed off with warm water.

From blackheads, against acne (comedones) and to prevent the appearance of acne, Aspirin can be used as part of a mask with coffee and clay. At 2 tbsp. tablespoons of white or blue cosmetic clay, it is recommended to use 1 teaspoon of medium-ground natural coffee and 4 tablets of ASA.

To the finished mixture, soda mineral water is poured in small portions in the amount necessary to obtain a thick slurry. The product is applied to the skin with slow massaging movements, covering all areas except the upper and lower eyelids. The exposure time is 20 minutes, after which the mask is washed off. To enhance the effect, problem areas can be wiped with an ice cube.

Aspirin for hair is mainly used as a remedy for dandruff. The easiest way to treat hair diseases is to use shampoo with ASA.

To prepare a healing composition, the amount of shampoo needed for one shampoo is measured in a separate container (it is better if it contains a minimum of dyes and fragrances), and then 2 crushed tablets of ASA (without coating) are added to it.

Overdose

Symptoms of an overdose of moderate severity are: tinnitus, nausea, hearing impairment, vomiting, confusion, dizziness, headache. These phenomena disappear with a decrease in the dose of the drug.

Severe overdose of aspirin is accompanied by hyperventilation, fever, metabolic acidosis, respiratory alkalosis, ketosis, cardiogenic shock, comaexpressed hypoglycemia, respiratory failure.

In such cases, the patient is hospitalized. Treatment includes taking activated carbon, lavage, control of CSR, forced alkaline diuresis to obtain urine pH values ​​in the range of 7.5-8.0, compensation for fluid loss, hemodialysis, symptomatic therapy.

Interaction

ASA enhances effects non-steroidal anti-inflammatory drugs (for this reason, doctors do not recommend taking Aspirin with other drugs of this group, for example, simultaneously with Paracetamol), non-narcotic analgesics, oral hypoglycemic drugs, indirect anticoagulants, Heparina, thrombolyticsinhibiting platelet aggregation, triiodothyronine, sulfonamides.

Reduces effects diuretics, uricosuric drugs, antihypertensive drugs.

GCS, alcohol and ethanol-containing drugs increase the damaging effect of ASA on the mucous membrane of the digestive canal, increase the risk of gastric and intestinal bleeding.

ASA increases the plasma concentration of Li preparations, barbiturates and digoxin.

The absorption of ASA worsens and slows down while taking the drug with Al and / or Mg-containing antacids.

Terms of sale

Without recipe.

Latin recipe for the drug (sample): Rp .: Tab. Acidi acetylsalicylici 0,1 No. 10 D. S. If you suspect AMI, take 1 tablet 2 times a day.

Storage conditions

Tablets should be stored out of the reach of children, protected from light and moisture.

Shelf life

Five years.

Special instructions

ASA may cause hypersensitivity reactions (e.g., seizure bronchial asthma (BA) or bronchospasm) Risk factors are a history of AD, nasal polyps, fever, chronic bronchopulmonary diseases, allergies (skin manifestations allergies, allergic rhinitis).

ASA is able to increase the tendency to bleeding, due to its inhibitory effect on aggregation platelet count. This should be taken into account when prescribing the drug to patients who have surgery (including a small one, for example, tooth extraction).

The drug is stopped 5-7 days before surgery. The doctor should be informed that the patient was taking Aspirin before surgery.

ASA reduces the excretion of uric acid from the body, which in predisposed patients can provoke an acute attack gout.

Aspirin - benefit or harm?

ASA is widely used as pain medication, antipyreticand anti-inflammatory. In lower doses, it is used to prevent the development of vascular complications.

Today, ASK is the only disaggregantwhose effectiveness when used in the acute period ischemic stroke (cerebral infarction) is supported by evidence-based medicine.

With regular intake of ASA, the risk is significantly reduced colorectal cancer, as well as prostate cancer, lungs, esophagus and throat.

An important feature of ASA is that it irreversibly inhibits COX, an enzyme that is involved in the synthesis of thromboxanes and Pg. Acting as an acetylating agent, ASA is attached to the residue of serine in the active center of the COX acetyl group. This distinguishes the drug from other NSAIDs (in particular, from ibuprofen and diclofenac), which belong to the group of reversible COX inhibitors.

Bodybuilders use the combination of “Aspirin-Caffeine-Broncholitin”As a fat burner (such a mixture is considered the progenitor of all fat burners). Housewives have found the use of ASA in everyday life: the product is often used to remove sweat stains from white clothes and to water the soil affected by the fungus.

You can use ASA for flowers: a crushed Aspirin tablet is added to water when they want to keep cut plants longer.

Some women use Aspirin tablets as a contraceptive: the tablet is administered intravaginally 10-15 minutes before PA, or it is dissolved in water and then douched with the resulting solution.

The effectiveness of this method of protection against pregnancy has not been investigated, however, gynecologists do not deny the right to its existence. At the same time, doctors note that the effectiveness of contraception using ASA is only about 10%.

There is also an opinion that with the help of Aspirin, you can terminate the pregnancy. Doctors, of course, do not welcome such methods, but advise in the event that a pregnancy is not planned and undesirable, nevertheless, in a timely manner, seek medical help for help.

Despite the large number of useful properties, the drug also has a notoriety. The suppression of COX activity provokes a violation of the integrity of the walls of the digestive canal and is a development factor peptic ulcer.

Also, dangerous ASA can be for children under 12 years old. In case of use if available in the child viral infection the drug can cause Reye's syndrome - a disease that poses a threat to the life of small patients.

Analogs of Aspirin

Matches for ATX Level 4 code:Aspirin-SCitropackCitramonCoficil PlusFarmadolAskofen-PTsefekon NAquacitramoneUpsarin UPSACitrapackAlka primThrombopolCitrapar

Structural analogues: Acetylsalicylic acid, Aspirin UPSA, Thrombo ass, Taspir, Fluspirin, Asprovit, Aspirin “York” (or "american aspirin”- in another way this drug is called).

What can replace aspirin?

Analogs with a close mechanism of action: Aspirin Complexfrom, Askofen-P, Citrapar, Sodium Salicylate, Coficil Plus, Asprovit-S, Aspagel, Alka Prim, AnGrikaps, Tsefekon N.

Which is better: Aspirin or Aspirin Cardio?

To the question, what is the difference Aspirin and Aspirin Cardio, doctors respond that the differences in the drugs are the dosage of the active substance (lower in Aspirin Cardio) and that Aspirin Cardio tablets are available in a special enteric coating that protects the mucous membrane of the digestive canal from the aggressive effects of ASA.

Aspirin and Aspirin Cardio have different indications for use. The first (it contains 500 mg of ASA) is used as pain medication, antipyretic and anti-inflammatory, Aspirin Cardio, the concentration of ASA in which 100 or 300 mg / tab., Is prescribed for prevention and treatment:

  • thrombosis and embolism after CABG, transdermal intravascular coronary angioplasty and other vascular operations;
  • myocardial infarction;
  • unstable angina pectoris;
  • passing blood flow disorders in the brain and stroke at the premorbid stage;
  • coronary artery thrombosisin patients at risk;
  • migraine (including for long-term prevention).

Can I give children Aspirin?

Children are recommended to give Aspirin from the age of 12.

Give to children at a temperature rising in the background viral infection drugs that contain ASA are prohibited, since ASA acts on the same structures of the liver and brain as some viruses.

So the combination of aspirin and viral infection may cause development Reye's syndrome - A disease in which the brain and liver are affected, and from which approximately one in five small patients dies.

Development risk Reye's syndrome increases in cases where ASA is used as a concomitant drug, but there is no evidence of a causal relationship in such cases. One of the signs Reye's syndrome is prolonged vomiting.

As a single dose, children under three years of age are usually given 100 mg, children four to six years old - 200 mg, and children seven to nine years old - 300 mg ASA.

The recommended dose for the child is 60 mg / kg / day, divided into 4-6 doses, or 15 mg / kg every 6 hours or 10 mg / kg every 4 hours. In children under the age of three, the drug in this dosage form is not used.

Alcohol compatibility

Can I drink Aspirin with alcohol?

Aspirin and alcohol are incompatible. There are descriptions of cases where even 40 g of alcohol in combination with the drug was accompanied by the development of gastric bleeding and severe allergic reactions.

Does Aspirin help with a hangover?

Aspirin for a hangover is very effective due to the ability of ASA to inhibit aggregation platelet count (both spontaneous and induced).

When asked whether it is possible to drink Aspirin with a hangover, doctors answer that it is better to use the drug not after alcohol, but about 2 hours before the planned feast. This will prevent microthrombosis in the small blood vessels of the brain and - in part - tissue edema.

For a hangover, it’s best to take the fast-dissolving Aspirin, for example Upsarin UPSA. The latter is less irritating to the gastrointestinal mucosa, and the citric acid contained in it activates the processing of under-oxidized alcohol decay products. The optimal dosage is 500 mg for every 35 kg of body weight.

Aspirin during pregnancy

Can I drink Aspirin during pregnancy in the early stages?

The use of salicylates in the first three months in individual retrospective epidemiological studies has been associated with an increased risk of developing birth defects (including heart defects and cleft palate).

However, with prolonged use of the drug in therapeutic doses that do not exceed 150 mg / day, this risk was low. In 32 thousand pairs of “mother-child" studies did not reveal a relationship between the use of Aspirin and an increase in the number of congenital malformations.

During pregnancy, ASA should be taken only after assessing the risk ratio for the baby / benefit for the mother. If long-term use of Aspirin is necessary, the daily dose of ASA should not exceed 150 mg.

Aspirin for pregnant women in the 3rd trimester

In the last months of pregnancy, taking high (more than 300 mg / day) doses of salicylates can cause pregnancy to delay and weaken contractions during childbirth.

In addition, aspirin treatment at such doses may lead to premature closure in the child. ductus arteriosus (cardiopulmonary toxicity).

The use of high doses of ASA shortly before birth can cause intracranial bleeding, especially in premature babies.

Based on this, except in exceptional cases due to obstetric and cardiological medical indications using special monitoring, the use of ASA in the last trimester of pregnancy is contraindicated.

Can I take Aspirin while breastfeeding?

Salicylates and their metabolic products penetrate into milk in a small amount. Since side effects in infants after accidental use of the drug were not observed, interruption of hepatitis B is usually not required.

If you need long-term treatment with the drug in high doses, it is necessary to decide on the termination of breastfeeding.

Reviews about Aspirin

Aspirin is a medicine that everyone knows. Its effectiveness has been clinically tested, and the safety profile and mechanism of action have been thoroughly studied. WHO has included ASA in the list of essential drugs.

The properties of ASA allow the use of Aspirin for the relief of pain and inflammation, to reduce fever and ICP, as well as for the prevention of vascular complications.

Along with reviews on the use of ASA for its intended purpose, women also leave good reviews about cleaning the face with Aspirin and reviews about the use of the drug for hair. A lot of positive reviews about the mask “Aspirin with honey”, which in cosmetology is used as a remedy for acne.

Aspirin well treats inflamed elements, relieves swelling of tissues and promotes exfoliation of dead cells, honey for the skin is useful in that, penetrating into the deeper layers, perfectly nourishes and cleanses the skin, prevents evaporation of moisture from the skin, has an astringent, firming and tonic effect.

Aspirin price, how much are tablets

The price of Aspirin 500 mg No. 10 in Russia is 225 rubles. Price Aspirin Cardio 300 mg No. 20 - from 80 rubles., 100 mg No. 28 - from 130 rubles. Buy fizzy Aspirin Bayer possible on average for 200 rubles. (price for 10 tablets) Upsarin UPSA - from 170 rub. for 16 tablets.

Drug cost Thrombo ass - from 45 rubles.

  • Online Pharmacies in Russia
  • Online pharmacies in UkraineUkraine
  • Online pharmacies in Kazakhstan

ZdravCity

  • Aspirin with tab. spike. n10 Bayer Bitterfeld GmbH
  • Aspirin Cardio Tab. PO Ksh / sol 100mg n56Bayer AG / Bayer Bitterfeld GmbH233 rub.

Pharmacy Dialog

  • Aspirin Cardio (tab. N / a 100mg No. 56) 222 rub.order
  • Aspirin Cardio tablets 100mg No. 28123 rub.order
  • Aspirin Bayer effervescent tablets No. 10 with vitamin C280 rub.order
  • Aspirin Express (tab. Ship. 500mg No. 12) 274 rub. Order
  • Aspirin Complex (pack 3.5475g No. 10) 467 rub. Order

Eurofarm * 4% discount on the promotional code medside11

  • Aspirin-s effervescent tablets 10 pcs. Bayer Bitterfeld GmbH 320 rub.
  • Aspirin complex powder n10 sachet Kern Pharma S.L. 550 rub.order
  • Aspirin cardio 100 mg No. 28 tabl Bayer Pharma AG / Bayer Bitterfeld148 rub.order
  • Aspirin cardio 100 mg No. 56 tablets Bayer Pharma AG / Bayer Bitterfeld252 rub.order
  • Aspirin cardio 300 mg n20 tablet Bayer Pharma AG / Bayer Bitterfeld 85 rub.
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Pharmacy24

  • Aspirin C No. 10 effervescent tablets Bayer Betterfeld GmbH, Nіmechchina68 UAH to order
  • Aspirin Cardio 100 mg No. 56 tablets Bayer Pharma AG, Nimechchina / Bayer Betterfeld GmbH, Nimechchina93 UAH order
  • Acetylsalicylic acid (Aspirin) 500 mg No. 10 tablets, PAT "Kyivmedpreparat", Ukraine / PAT "Galichpharm", Ukraine7 UAH order
  • Acetylsalicylic acid (Aspirin) 500 mg No. 10 tablets PAT "Lubnifarm", Ukraine 3 UAH order
  • Aspirin 500 mg N10 tablets Bayer Betterfeld GmbH, Nimechchina39 uah.

Pani Pharmacy

  • Aspirin cardio tablets Aspirin cardio tablets 300mg No. 28 Germany, Bayer Bitterfeld 92 uah. Order
  • Aspirin tablets Aspirin tablets 500mg No. 10 Germany, Bayer Bitterfeld 41 UAH order
  • Aspirin cardio tablets Aspirin cardio tablets 100mg No. 28 Germany, Bayer Bitterfeld 61 UAH order
  • Aspirin tablets Aspirin tablets 500mg No. 20 Germany, Bayer Bitterfeld 73 UAH to order
  • Aspirin cardio tablets Aspirin cardio tablets 100mg No. 56 Germany, Bayer Bitterfeld 99 uah. Order
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BIOSPHERE

  • Aspirin Cardio 100 mg No. 30 tablets of a solution / intestine Bay Pharma (Germany) 1 tg.
  • Aspirin Cardio 100 mg No. 28 tablets, solution / intestine Bay Pharma (Germany) 1 tg.
  • Agrippin SR with aspirin No. 10 table.Zhanafarm (Kazakhstan) 150 tg.order
  • Aspirin-S No. 10 tablets. Bayer Consumer Car AG, Switzerland, manufactured by Bayer Bitterfeld GmbH (Germany) 1 tenge to order
  • Aspirin Cardio 300 mg No. 30 tablets of a solution / intestine Bay Pharma (Germany) 1 tg.
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