100 ml of solution include 100 mg hexetidine; 500 mg choline salicylate; 250 mg chlorobutanol hemihydrate - active ingredients.
Additional ingredients: polysorbate, sodium saccharin, propionic acid, 96% ethanol, menthol, methyl salicylate, eucalyptol, purified water, oils (peppermint, anise, lemon).
Angilex is available in the form of a spray of 30 ml; 50 ml and 120 ml solution.
Analgesic, antiseptic, anti-inflammatory, antifungal, antibacterial.
Pharmacodynamics and pharmacokinetics
Angilex-Health is a complex drug used for sore throat. The pharmacological effectiveness of the drug is achieved through the action of its three active ingredients - chlorobutanol, choline salicylate and hexetidine.
Antifungal and antibacterial efficacy inherent in the substance hexetidine in relation to many anaerobicand aerobic microorganismsboth positively and negatively colored by Gram method. Weak bactericidal and bacteriostatic effect hexetidinemanifests in relation to aerobic microorganisms, and a persistent bactericidal effect is observed in relation to anaerobic bacteria. A characteristic feature of the mechanism of action hexetidine, due to the similarity of chemical structures, is its ability to competitively replace thiaminewhich is necessary for development microorganisms.
Anti-inflammatory and analgesic efficacy due to exposure to a group drug NSAIDs- choline salicylate and local effects anesthetic - chlorobutanolwhich is used in otolaryngology(rinses, drops in the nose) and in dentistry (irrigation, applications), mainly with analgesic purpose.
When using Angilex solution or spray, its active ingredients are fixed on the mucous membranes of the mouth and throat and are gradually released and have a therapeutic effect.
Indications for use
The use of Angilex is indicated for topical treatment of painful conditions of the throat and oral cavity of inflammatory etiology:
- sore throats;
- tonsillitis(chronic and acute);
- teething pain;
- oral care (in the postoperative period).
- atrophic pharyngitis;
- age up to 2.5 years;
- bronchial asthma or any other respiratory diseases associated with their hypersensitivity;
- heightened personal sensitivity to the ingredients of drugs.
The immune system
- Quincke's edema;
- skin manifestations;
- other allergic effects.
- olfactory disorders;
- taste disorders (including dysgeusiaand Agevzia).
- dry mouth
- pain when swallowing;
- gastrointestinal tract disorders, including nausea, dyspepsia, vomit(if swallowed).
- skin rashes;
- contact allergic dermatitis.
- sensation numbness;
- color changes in the tongue and / or teeth;
- feeling burning;
- feeling of heat, soreness, itching mucous membranes of the mouth or tongue;
- paresthesia mucous membrane;
- ticklein the throat;
- decreased receptor sensitivity;
- mucosal inflammation;
- vesicles in the throat;
- mucosal manifestations;
- swelling at the point of contact with the drug;
- dry throat / nose mucosa.
In case of occurrence of any negative phenomena, the use of Angilex should be interrupted and your doctor should be informed.
Angilex, instructions for use
The spray is intended for topical use for irrigation of the oral cavity.
Adult patients are advised to do 4-6 sprays in 24 hours. Children after 2.5 years are shown conducting 2-3 sprayings per day. The use of the spray is best limited to five days.
The solution is also a topical agent and is used to rinse the oral cavity. For the rinsing procedure, 2 teaspoons of the solution should be displaced with 50-75 ml of warm boiled water, after which, for several seconds, avoiding swallowing, rinse the oral cavity. The use of the solution is best limited to five days.
Theoretically, due to inclusion ethanolwith excessive use or ingestion of the drug may form alcohol intoxication.
Percentage hexetidinein the drug, in the case of the use of Angilex according to the recommendations, can not have toxic action.
Also, with uncontrolled use or ingestion of a drug, the development or deepening of existing side effects can be observed.
In these cases, it is recommended to immediately stop taking any form of the drug and conduct treatment that is consistent with the observed symptoms.
Do not use with others antiseptic drugsdue to possible cross-reactions.
Please note that when using alkaline solutions effects are inactivated hexetidine.
Terms of sale
Purchasing Angilex does not require a prescription.
The spray and solution of the drug must be stored in the manufacturer's primary packaging (up to 25 ° C).
From the date of manufacture - 3 years.
Due to the inclusion of drugs ethanol it is necessary to exclude the ingestion of the drug and its contact with the eyes, and also with caution, assign it to patients with liver pathologies.
The use of drugs for a long period of time is not recommended, since this can lead to a change in natural microbial balance oral cavity / throat, which can cause secondary fungal and / or bacterial spread.
In case of clinical symptoms bacterial infection general antibiotic therapy.
While maintaining the symptoms of the underlying disease for more than 5 days of treatment or fever therapy should be reviewed.
Since Angilex can reduce epileptic threshold and give rise to seizures(especially in children), it should be used with extreme caution in patients with epilepsy.
Also, caution is required for patients with manifestations allergic reactions and especially patients with a proven allergy to Aspirin (acetylsalicylic acid).
Due to the presence in the preparation menthol there is a risk of laryngospasm(especially in children).
In case of treatment failure and amplification sore throattreatment with Angilex is discontinued.
- Aqua Maris;
- Angi Sept;
- Rinza Lorsept;
- Efizol etc.
- Flucytron ENT;
Due to the lack of experience in use, it is not prescribed up to 2.5 years.
During the use of Angilex, it is better to stop drinking alcohol.
In pregnancy (and lactation)
Use of Angilex with of pregnancy and breastfeeding possible only on the recommendation of a doctor.
People using this drug mostly leave positive reviews about Angilex. According to them, the effectiveness of the drug is at a fairly high level and, importantly, without the manifestation of any side effects. Of the negative comments can be identified taste qualities a drug where one doesn't like the aftertaste alcoholand to others menthol. Also, a small number of patients observed some other negative effects of the drug that took place after cessation of its use.
In general, the Angilex drug has shown its good side and is recommended for use by many experts in the field of otolaryngology.
Price, where to buy
The average price of Angilex is:
- spray 30 ml - 50 hryvnia;
- spray 50 ml - 60 hryvnia;
- 120 ml solution - 50 hryvnias.
- Online pharmacies in UkraineUkraine
- Angileks liquid Angileks-Health spray d / mouth.cavities fl.50ml Ukraine, Health LLC 67 UAH.order
- Angileks liquid Angileks-Health spray d / mouth.cavities fl.30ml Ukraine, Health LLC 66 UAH order
- Angileks liquid Angileks-Health r-r d / mouth.cavities fl. 120ml Ukraine, Health LLC 58 UAH order