One tablet of Cytotec includes 200 mcg misoprostol.

Additional substances: castor oil, sodium carboxymethyl starch, microcrystalline cellulose, silicon dioxide.

Release form

Serrated white cylindrical tablets.

10 tablets in a blister; one, two, five or three blisters in a cardboard box.

Pharmachologic effect


Pharmacodynamics and pharmacokinetics


Cytotec tablets are related to antisecretory, antiulcer drugsand also have cytoprotective properties.

Misoprostol is an artificial analogue Prostaglandin E1, which has a protective effect on the mucous membrane of the intestines and stomach. Increases the resistance of the inner lining of the stomach to the action of negative factors: poor nutrition, alcohol, stress, anti-inflammatory non-steroidal drugs; promotes tightening peptic ulcersstops the appearance of erosive and ulcerative disorders.

The cytoprotective effect of the drug is associated with an increase in the production of mucus in the stomach and an increase in the intrinsic secretion of bicarbonate of the gastric mucosa. The drug also has antisecretory activity, reacting with receptors E-type prostaglandin. It has a direct effect on the cells of the stomach, inhibits nocturnal, basal and stimulated secretion of hydrochloric acid, reduces the amount and proteolytic activity of gastric juice. Weakens basal products endogenous pepsin. Enhances blood flow in the membranes of the stomach. The action of the drug begins half an hour after administration and lasts at least 3 hours. The effect has a pronounced dose-dependent nature. Increases the strength and frequency of contractions of the myometrium and intestinal muscles.


It is quickly absorbed (food intake inhibits absorption). In the walls of the intestines and in the liver misoprostolbiotransformed with the formation of pharmacologically active misoprostolic acid. The highest concentration is created after about 12 minutes, circulates in the vascular bed in complex with proteins (up to 90%). The elimination half-life can reach 40 minutes. The equilibrium concentration of the active substance in blood achieved after 2 days, accumulation is not observed. Up to 80% of the dose taken is excreted by the kidneys, if their functioning is impaired, it is possible to increase the half-life and increase the maximum concentration by 2 times.

Indications for use

  • Treatment and prevention of lesions of the mucous membranes of the stomach and duodenum of an erosive-ulcerative nature, including those caused by taking anti-inflammatory non-steroidal drugs.
  • Drug interruption of pregnancy (with medication abortion in most countries, the medicine is used without official permission and without information necessary for the patient about safe use).


  • Cardiovascular disease.
  • Hypersensitivity to the components of the drug.
  • Lesions of the liver and kidneys.
  • Endocrinopathies and endocrine damage.
  • Diseases Associated with Addiction prostaglandins.
  • Anemia.
  • Hormone-dependent tumors. +
  • Period lactation.
  • Age to 18 years.
  • Suspicion on ectopic pregnancy.
  • The use of intrauterine contraceptives.
  • Pregnancy (if the drug is not used to interrupt it).

Side effects

  • Digestive disorders: abdominal pain, vomiting, diarrhea, dyspepsianausea flatulence, constipation.
  • Genital disorders: pain in the lower abdomen, hypermenorrhea, dysmenorrhea, postmenopausal vaginal discharge of a bloody nature.
  • Other disorders: headache, cramps in women in paraclimacteric period, astheniafatigue, change in body weight, rash.

Instructions for use (Method and dosage)

The instructions on Saitotek provide for the use of the drug only for the treatment and prevention of peptic ulcer and does not extend the recommendations for the use of means to terminate pregnancy. The drug is taken orally during meals.

For treatment ulcers caused by use anti-inflammatory non-steroidal drugs, instructions for Cytotec prescribe to take 800 mcg of the drug twice a day for 1-2 months.

For warning ulcers caused by the use of anti-inflammatory non-steroidal agents, the medicine is taken at 200 mcg 2-4 times a day for the entire period of treatment anti-inflammatory non-steroidal agents.

Cytotec for abortion

Use for abortion up to 63 days is made only in combination with Mifepristone, trained by specialists in special medical institutions with the possibility of emergency assistance. In later terms, the drug is ineffective.


No toxicity data misoprostol in humans. Symptoms of excess dosage: drowsiness, bradycardiacramps tremorabdominal pain palpitations fever, arterial hypotension.


When combined with antacidsthe concentration of the active substance in the blood decreases.

When used simultaneously with magnesium-containing antacids gain is not excluded diarrhea.

When combined with Diclofenac or Indomethacin side effects of the latter are stimulated.

Terms of sale

On prescription.

Storage conditions

Store in a dry place at temperatures up to 30 ° C. Keep out of the reach of children.

Shelf life

3 years.

Special instructions

The medicine should be prescribed with caution to patients with coronary heart disease, arterial hypotension,circulatory disorders diarrhea, epilepsy, coronary cardiosclerosis, enterocolitis, hypersensitivity to prostaglandins.

When appointing patients of reproductive age, it is necessary to preliminarily pregnancy test. The test should remain negative for 2 weeks before using the drug. Treatment is allowed to start only 2 days after the onset of menstruation. Throughout the entire period of admission, reliable methods of preventing pregnancy should be used. Misoprostol increases the tone of the uterus and is capable of provoking a miscarriage.


Misoprostol, Misoprostol-GPMC, Mirolyut.

For children

Not used in individuals under 18 years of age.

In pregnancy (and lactation)

The drug is not allowed to be used during these periods, except when used to terminate a pregnancy.

Reviews about site library

The most common reviews about the drug when used to terminate a pregnancy. These reports show that in many cases the drug was ineffective and there was a need for additional surgical and gynecological procedures and even surgical intervention. It is strictly forbidden to use the drug on its own and outside special medical institutions because of the potential threat to the patient's life.

Price Cytotec where to buy

The price of Saitotek No. 10 in Russia is about 1300 rubles, and packaging number 20 is about 2850 rubles. It is quite difficult to buy a drug in Moscow or another city with the potential for independent use to terminate a pregnancy.

In Ukraine, the price of medicine number 50 reaches 1800 hryvnia.

  • Online Pharmacies in Russia

LuxPharma * special offer

  • Cytotec tablets 200 mcg No. 603900 rub.order
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Watch the video: MyExperience With Cytotec (February 2020).

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