One tablet contains the active ingredient: Fosinopril Sodium.
Auxiliary components: lactose monohydrate, pregelatinized corn starch, croscarmellose sodium, MCC and glycerol dibehenate.
Fozicard is available in the form of tablets, which contain 5, 10 or 20 mg of the main substance, packaged in 10 pieces in a blister pack, enclosed in 3 pieces in a pack.
The drug has vasodilating and hypotensive action.
Pharmacodynamics and pharmacokinetics
The drug has a pronounced antihypertensive and vasodilating effect. Its main component is metabolized inside the body, resulting in the formation of a pharmacologically active substance - fosinoprilat. The mechanism of therapeutic action is manifested by inhibition of activity angiotensin converting enzymethat allows you to prevent the transition angiotensin-I at angiotensin IIwith a marked vasoconstrictor effect. Decay also slows down. bradykininable to dilate blood vessels. In this case, the total peripheral vascular resistance decreases, decreases arterial pressure, pre- and afterload on myocardium.
These tablets are well absorbed in the digestive tract. The development of a therapeutic effect occurs within an hour, the maximum concentration is reached after 2-6 hours and lasts about 24 hours, even with a single application. Long-term use does not contribute to the development of tolerance to fosinopril. This substance is characterized by an increased degree of binding to plasma proteins, about 95%. Breeding fosinoprilat occurs with the help of the kidneys and liver. On average, the elimination half-life reaches 11.5 hours.
The main indications for the use of Fozikard:
- chronic heart failure;
- arterial hypertension.
It is not recommended to take this drug with:
- hypersensitivity to fosinopril and other components;
- hereditary or idiopathic angioedema;
- lactation, pregnancy;
- under the age of 18 years.
Caution is necessary when:
- renal failure;
- bilateral stenosis of the renal arteries and arteries of a single kidney;
- condition after kidney transplantation, desensitization, some systemic diseases of connective tissues;
- cerebrovascular diseases, for example, cerebrovascular insufficiency;
- diabetes mellitus;
- aortic stenosis;
- inhibition of bone marrow hematopoiesis;
- old age and so on.
When treating with Fozicard, side effects may occur that affect the activity of all systems and organs. For example, the cardiovascular system can respond by lowering blood pressure, orthostatic hypotension, tachycardia, palpitations, arrhythmias, angina pectoris, myocardial infarction and chest pain.
Deviations in operation are also possible. digestive system in the form of nausea, vomiting, constipation, intestinal obstruction, pancreatitis, hepatitis, stomatitis, glossitis, dyspepsia, abdominal pain, anorexia and so on.
In addition, the occurrence of violations associated with activities respiratory, urinary and nervous systems.
The probability of defeat remains aboutsensory organs, the development of allergic reactions and changes in laboratory parameters.
Fosicard - instructions for use (Method and dosage)
Fozicard tablets are intended for oral administration. Usually, the dosage and duration of treatment are selected individually, but there are a number of standard rules.
According to the instructions for use of Fozikard, during therapy arterial hypertension It is recommended to stop taking any antihypertensive drugs in advance.
The initial daily dosage of this drug is 1 time in 10 mg. In the future, dose selection is required taking into account blood pressure indicators. In this case, the maintenance daily dose may be 1 time in 10-40 mg. If monotherapy with Fozicard does not bring a positive effect, then admission is permissible diuretic.
When do you start taking this drug with diuretic, then an initial dose of up to 10 mg is prescribed, carrying out careful medical monitoring of the patient's condition.
During therapy for chronic heart failure, an initial daily dose of 10 mg is established. Gradually perform a weekly dose increase of 10 mg. In this case, the maximum dosage should not be higher than 40 mg / day. Reception is also possible. diuretic.
Cases of overdose can cause a marked decrease in blood pressure, bradycardia, shock, disturbance of water-electrolyte balance, acute renal failure or stupor.
In this case, it is required to stop the use of Fozikard, lay the patient, raising his legs and conduct symptomatic treatment. In mild cases of overdose, gastric lavage, application will be sufficient adsorbents, sodium sulfate.
Concomitant use of the drug with hypotensive means diuretics, narcotic analgesics, general anesthesia able to strengthen hypotensive effect fosinopril.
Combination with potassium preparations and some potassium-sparing diuretics increase the likelihood of development hyperkalemia. Simultaneous use with lithium salts increases the concentration of lithium in the blood.
Fosicardum increases the hypoglycemic effect of sulfonylurea derivatives, insulin, the risk of leukopenia in cases of simultaneous use with allopurinol, immunosuppressants, cytostatic drugs, procainamide. The combination with NSAIDs and estrogens reduces the severity of the hypotensive effect.
Fosicard treatment of severely ill patients arterial hypertension or decompensated chronic heart failureIt is recommended to start in a hospital. Moreover, the therapeutic process requires control of blood pressure, renal function, and maintenance hemoglobin, urea and creatinine, the concentration of electrolytes and potassium, the activity of liver enzymes in the blood.
Also periodically need to control the number white blood cellsespecially if there is a risk neutropenia, for example, in cases of impaired renal function or systemic diseases of the connective tissues.
A possible increase in the development of arterial hypotension requires caution when the drug is prescribed to patients who are on a salt-free or low-salt diet.
Taking this drug may cause dizziness, usually at the beginning of treatment when combined with diureticsTherefore, care must be taken in activities requiring special attention or when driving vehicles.
Terms of sale
Fosicard is a prescription.
For storage of tablets, a dark place is intended at a temperature of up to 30 C, well protected from children.
Fozikard's analogsMatches for ATX Level 4 code:DilaprelPrenesaEnapDirotonLiprilReniprilParnawelFozinapTritaceEnamZokardisFosinoprilLisinoprilCaptoprilMonoprilRenetekHartilAmprilanRamiprilPerindopril
The main analogues are represented by drugs Monopril, Fosinotec and Fosicard H. Also have a similar effect: Enalapril, Prestarium, Captopril and Lisinopril.
Fosicard N tablets
The difference of this drug lies in its composition, which includes fosinopril sodium and additional substance - hydrochlorothiazide. This leads to its pharmacological action - hypotensive, potassium-sparing, vasodilating and diuretic.
During treatment with Fozicard, it is recommended to refrain from drinking alcohol, which can reduce its hypotensive effect.
Reviews about Fozikarda
This drug is usually prescribed for hypertension, but it should be understood that such treatment does not bring complete recovery. At the same time, reviews of Fizikard show that complex therapy with this agent is carried out by patients who have been troubled by such a disease for several years.
According to experts, the treatment of hypertension requires the right approach and perseverance. Therefore, patients must follow the doctor’s prescription without violating the therapeutic regimen and without stopping treatment on their own. In addition to taking medications, you must adhere to a healthy lifestyle, perform procedures that strengthen blood vessels.
Fozikard price where to buy
The price of Fozikard varies between 107-237 rubles and depends on the content in tablets of the amount of active substance.
- Online Pharmacies in Russia
- Online pharmacies in UkraineUkraine
- Online pharmacies in Kazakhstan
- Fosicard Tab. 20mg n28Actavis hf./HFZ Zdravle AD-Leskovac 288 rub.order
- Fosicard n tab. 20mg + 12.5mg n28Zdravle-Leskovac AO HFZ373 rub.order
- Fosicard (tab. 5mg No. 28) 166 rub.order
- Fozicard (tab. 20mg No. 28) 294 rub.order
- Fosicard N (tab. 20 / 12.5mg No. 28) 391 rub.
- Fozicard (tab. 10mg No. 28) 215 rub.order
Eurofarm * 4% discount on the promotional code medside11
- Fosicard 10 mg No. 28 tabl.KHFZ Zdravle AD320 rub.order
- Fosicard 5 mg No. 28 tabletsZdravle HFZ AD-Leskovac199 rub.order
- Fosicard n 20 mg + 12.5 mg No. 28 tab.Zdravle HFZ AO480 rub.order
- Fosicard 20 mg No. 28 tabletZdravle HFZ AD-Leskovac 360 rubles to order
- Fosicard 20 mg No. 30 tablets Actavis AT.Island / Pharmacy.Industria, Zdravl AT, Serbia / Balkanpharm-Dupnitsya AT, Bulgaria204 UAH order
- Fozicard 10 mg No. 30 tablets Actavis AT.Island / Pharmaceutical and Industrial India, Health AT, Serbia158 UAH order
- Fosicard H tablets Fosicard H tablets 20 / 12.5mg No. 30 Iceland, Actavis 174 UAH order
- Fosicard tablets Fosicard tablets 20mg No. 30 Serbia, Zdravlje 205 UAH order
- Fosicard tablets Fosicard tablets 10mg No. 30 Serbia, Zdravlje 152 UAH order
- Fosicard N No. 28 table.Balkanpharma-Dupnitza AD (Bulgaria) 2 tg.order
- Fosicard 10 mg No. 28 tablets Zdravle A.D. (Serbia) 2 tg.order
- Fosicard 20 mg No. 28 tablets Zdravle A.D. (Serbia) 2 tg.order