Medication

Klenzit

Structure

1 gram of gel contains 1 mg Adapalena - active substance.

Auxiliary ingredients:

  • propylene glycol;
  • disodium edetate;
  • methyl parahydroxybenzoate;
  • carbomer 940 (carbopol 940);
  • phenoxyethanol;
  • sodium hydroxide;
  • poloxamer 407;
  • purified water.

Release form

The drug is available in the form of a gel for external use.

The package contains 1 tube of 0.1% gel of 15 g or 30 g.

Pharmachologic effect

Anti-inflammatory, comedonolytic.

Pharmacodynamics and pharmacokinetics

Topical drug Klenzit gel is intended for the treatment ofacne. The active substance of the drug is retinoid derivative - Adapalen,showing anti-inflammatory and comedonolytic activity. Adapalene takes part in the normalization of processes epidermal differentiation and keratinizationinhibits education micro comedones and reduces manifestations inflammatory process.

The mechanism of action of the active substance of the drug Klenzit lies in its ability to influence specific gamma receptors of cells epidermis of the skin, lowering their adherence at the mouths of the sebaceous hair follicles.

In vivo and in vitro studies have shown that Adapalen has a pronounced anti-inflammatory effect, due to its effect on factors of the inflammatory process. Depressing arachidonic acid metabolism and leukocyte migration.

For external use of the gel systemic absorption its active substance Adapalenaquite low, about 4% of the dose used.

From the systemic circulation, excreted by the liver.

Indications for use

Acne (acne).

Contraindications

  • hypersensitivity to Adapalen and other ingredients of the drug;
  • period lactation;
  • period of pregnancy.

Use with caution when eczema and dermatitis.

Side effects

Klenzit gel therapy is generally well tolerated. In rare cases, observed hyperemia, irritation, peeling of the skin. In the event of these complications, it is recommended to temporarily suspend therapy, with resumption after the disappearance of these effects.

Isolated cases of development are described. allergic manifestationsthat were the reason for the complete withdrawal of treatment.

Instructions for use (Method and dosage)

The drug is used exclusively topically (externally).

Before applying the gel, the instruction for Klenzit recommends thoroughly clean and dry the problem areas of the skin of the face.

With light touches, evenly spread the gel on the affected surface blackheads. Apply the drug Klenzit 1 time per day, preferably in the evening, while trying not to hurt the nasal cavity and mouth, as well as the mucous membrane of the eye.

The therapeutic effect is observed 1-2 months after the start of treatment and reaches a lasting positive effect after 3 months of therapy.

In rare cases, due to passing skin irritationtreatment may be suspended until symptoms disappear irritation.

After consultation with your doctor, you can prescribe a second course of therapy.

Overdose

With external use of the drug, an overdose is unlikely.

In case of accidental internal administration of the gel, standard therapy with gastric lavage and prescription is performed. enterosorbents.

Interaction

When applying the drug Klenzit in the evening, it is permissible to use other anti-acne drugs the next morning.

The simultaneous use of Klenzit gel and products with drying and irritating properties (cologne, alcohol solutions) is not recommended.

Joint assignment with Benzoyl peroxide and clindamycin.

Terms of sale

On prescription.

Storage conditions

At a temperature not exceeding 25 ° C.

Shelf life

24 months.

Special instructions

In case of accidental ingestion of the drug in the mouth and nose, as well as on the mucous membrane of the eye, it is necessary to rinse them with special care with warm water.

It is recommended to avoid the influence of direct sunlight on the skin areas with the gel, because of the possible development skin irritation.

Analogs

Matches for ATX Level 4 code:AdaklinIsotrexinAdapaleneDifferinEffezelRetinoic OintmentRetin ARadevitWe see

Analogs of the drug Klenzit, which can replace it in case of individual sensitivity to its active substance:

  • Isotrexin;
  • Acnestop;
  • We see
  • Radevit;
  • Effezel;
  • Retinoic ointment.

Synonyms

  • Adapalene;
  • Differin;
  • Adacline
  • Adolen.

In pregnancy (and lactation)

The use of Klenzita during pregnancy and breastfeeding is contraindicated.

Reviews about Klenzit

Looking through various pages of sites devoted to the problem of facial skin and in particular acne (acne) It can be noted that when considering local medicines that help get rid of acne, reviews about Klenzit are mostly positive. Of course, if you want to overcome this problem at a time, then this drug is not for you. The treatment process is quite long (a persistent effect occurs after 3 months of use) and requires additional efforts to care for the skin of the face, since after applying the drug often dry skin that needs to be moisturized. Gel Klenzit is very economical and therapy with its application allows parallel use, after a break, other dermatological agents.It is worth noting that Klenzit is not suitable for everyone, so before you start treatment acneconsult with a dermatologist who, in case of any contraindications, may prescribe the appropriate analogue.

The difference between Klenzit and Klenzit S

The main difference between these drugs is that Klenzit C gel contains, in addition to Adapalenabeing retinoid metabolite, bacteriostatic antibiotic - clindamycinactive against purulent inflammation caused by some gram-positive cocci.

During therapy acnesubject to a positive reaction of the body to Adapalene and Clindamycin, it is best not to choose between Klenzit or Klenzit C drugs, but to use them in general treatment. First, use Klenzit C for about 2 weeks, then switch to Klenzit.

Klenzit's price where to buy

The price of gel in pharmacies in Russia is approximately: 15 g - 350 rubles and 30 g - 500 rubles.

The price of Klenzit in Ukraine varies at the level of 340 hryvnias for 15 g and 450 hryvnias for 30 g.

  • Online Pharmacies in Russia

ZdravCity

  • Klenzit gel 0.1% 30gGlenmark Pharmasyyutikalz LTD614 rub.order
  • Klenzit gel 0.1% 15gGlenmark Pharma434 rub. Order
  • Klenzit-s gel 30gGlenmark Pharmasyyutikalz LTD766 rub.order

Pharmacy Dialog

  • Klenzit-S gel tube 15g604 rub.order
  • Klenzit-S gel (tube 30g) 840 rub.order
  • Klenzit gel tube 30g630 rub.order
  • Klenzit 0.1% gel tube 15g398 rub.order

Eurofarm * 4% discount on the promotional code medside11

  • Klenzit gel 30 gGlenmark Pharmasyyutikalz Ltd760 rub.order
  • Klenzit gel 15 gGlenmark Pharmasyyutikalz Ltd540 rub.order
  • Klenzit-s gel 15 gGlenmark Pharmasyyutikalz Ltd680 rub.order
  • Klenzit-s gel 30 gGlenmark Pharmasyyutikalz Ltd 970 rub.order
show more

Watch the video: Anti Acne Gel for Pimple Breakout. Adapalene Clindamycin Phosphate. Hey Berty (December 2019).

Popular Posts

Category Medication, Next Article

Angelique
Medication

Angelique

Composition Estradiol hemihydrate, drospirenone, corn starch, lactose monohydrate, pregelatinized corn starch, magnesium stearate, macrogol, povidone, talc, iron dye red oxide, titanium hypromellose dioxide. Release form: Round-shaped tablets are biconvex, gray-pink in a film coating in a blister in a cardboard bundle No. 28 and 84.
Read More
Relief
Medication

Relief

Composition of Relief The composition of this drug depends primarily on the form of release of the drug. The composition of suppositories (in one rectal suppository, 5 mg) of Relief contains 5 mg of the highly active active compound of phenylephrine hydrochloride, as well as such auxiliary components as cocoa bean oil, propyl parahydroxybenzoate, oil obtained from shark liver, corn starch and methyl parahydroxybenzoate.
Read More
Fosicard
Medication

Fosicard

Composition One tablet contains the active ingredient: Fosinopril Sodium. Auxiliary components: lactose monohydrate, pregelatinized corn starch, croscarmellose sodium, MCC and glycerol dibehenate. Release form Fozicard is produced in the form of tablets, which contain 5, 10 or 20 mg of the main substance, packaged in 10 pieces in blister packs, enclosed in 3 pieces in a pack.
Read More
Proudox
Medication

Proudox

Composition The drug contains the active substance aprotinin and additional components: benzyl alcohol, NaCl, water for injection. Gordox release form is made in the form of a solution for intravenous administration, 10,000 KIE / ml. Contained in a clear glass ampoule with a break point.
Read More