Composition Elevit Pronatal
The main active component of this pharmaceutical product is a vitamin complex, which includes such biological substances as:
- vitamin A (retinol palmitate) - 3600 IU (international units);
- vitamin b1 (thiamine mononitrate) - 1.6 mg;
- vitamin B2 (riboflavin) - 1.8 mg;
- vitamin b5 (calcium pantothenate) - 10 mg;
- vitamin b6 (pyridoxine hydrochloride) - 2.6 mg;
- vitamin b9 (folic acid) - 0.8 mg;
- vitamin b12 (cyanocobalamin) - 4 mcg;
- vitamin c (ascorbic acid) - 100 mg;
- vitamin D (cholecalciferol) - 500 IU;
- vitamin e (dl-a-tocopherol acetate) - 15 mg;
- vitamin PP (nicotinamide) - 19 mg;
- vitamin B7 (biotin) - 0.2 mg.
The composition of vitamins in each tablet of the drug is supplemented by a large number of various minerals, trace elements and their salts:
- pantothenate and calcium phosphate - 125 mg;
- phosphorus - 125 mg;
- stearate and magnesium phosphate - 100 mg;
- iron fumarate - 60 mg;
- zinc sulfate - 7.5 mg;
- copper sulfate - 1 mg;
- manganese sulfate - 1 mg.
The composition of the film shell:
- polyethylene glycol 6000 and 400;
- Precirol Ato 5;
- microcrystalline cellulose (MCC);
- sodium carboxymethyl starch;
- povidone K 30 and K 90;
- lactose monohydrate;
- magnesium stearate;
- ethyl cellulose.
Vitamin complex Elevit Pronatal in pharmacy kiosks is presented in the form of oblong tablets, film-coated, which are fixed in blisters of aluminum foil or PVC for 10 or 20 pieces.
Gray-yellow tablets have a biconvex shape with a characteristic strip for breaking on one of the surfaces. An odor may be detected that does not indicate the unsuitability of the pharmaceutical product. Cardboard packaging holds 3 or 10 blisters for 10 tablets or 5 blisters for 20 pieces.
The medicinal effects of the pharmaceutical preparation Elevit Pronatal should not be considered comprehensively, but in accordance with the constituent components, since all vitamins, trace elements and their derivatives are biologically active substances.
The main physiological role Vitamin A - this is the coordination of the normal formation of lipids, proteins and mucopolysaccharides in the proportions that are required proliferating tissue. Due to this property, the body's ability to reparations and regeneration damaged areas. Also, the vitamin provides the normal condition of the skin and mucous membranes, since in large quantities it is found in connective tissue and upper layers epithelium. The constituent Elevita improves functioning visual apparatus, in particular the operation of the eyes in low light ("twilight vision"), as it stimulates metabolic processes in the rods, retinal receptor cells.
Second name Vitamin B1 - antineuritic, since this active component normalizes the functioning of the nervous system, promotes physiological renewal myelin sheath nerve trunks and the natural course of electrical impulses. He is also involved in heart regulation - normalizes heart rate and strengthens muscle cells of the organ. Vitamin is a stimulating factor in blood formation, which ensures timely blood composition updates and improves its microcirculation. As coenzymeor a specific carrier is involved in carbohydrate, protein, fat and water-salt metabolism.
Vitamin B2 is an indispensable part of the normal cycle of formation of red blood cells (red blood cells) and antibodies. It has a beneficial effect on the mucous membrane of the digestive tube and respiratory tract, as it contributes to its strengthening and timely renewal of epithelial cover. Eliminates the effects of toxins that enter the body through the respiratory tract. Participates in the physiological development of tissues and organs of the fetus.
Pyridoxine hydrochloride or vitamin b6 found in many metabolic processes. First of all, it lowers the concentration cholesterol and low and very low density lipids in the blood, showing antiatherogenic effect. It helps to improve the contractility of the heart muscle, as it increases the intake of beneficial nutrients. Normalizes the functioning of the central and peripheral nervous system, activating a more intense axonal transport and trophic neurons. Strengthens the cellular structure of bone tissue, teeth, gums and appendages of the skin (hair and nails). Stimulates hematopoiesis.
Cyanocobalamin- an indispensable element for the formation of normal blood cells. In conjunction with Hageman factorlocalized on the surface of the stomach, is involved in the absorption of iron through active diffusion and its transport to the place of synthesis of the main blood cells - red blood cells. This increases the intensity oxygen exchange and improved gas delivery to peripheral tissues and organs. In the absence of vitamin B12, macrocytic development megaloblastic anemia, since the physiological structure of red blood cells is disturbed. Also, the biologically active component normalizes circadian rhythmsimproving sleep and adjusting wake hours.
Vitamin C is a powerful antioxidant factor of a natural nature. By binding free radical structures, it protects the cell wall from their damaging effects. Due to the stimulating effect on the immune system own resistance to infectious diseases increases, therefore it is recommended to be taken abundantly in the winter, when ARVI threatens everyone and everyone. Ascorbic acid is also involved in maturation. connective tissuecontributing to the metabolic cycle proline. Thus, the vitamin plays a role in bone formation, gums, teeth, strengthening the vascular wall of the microvasculature. Participating in the digestive chain contributes to the normal absorption of calcium and iron.
Key role vitamin D3lies in regulation calcium metabolism and phosphorusin the body. Due to its pharmacological effects, trace elements are better absorbed from food products in the gastrointestinal tract, are timely deposited in bone tissue and dentin, and their renal excretion is delayed. The complex effect of vitamin resist osteomalaciaand softening bone tooth decaydue to influences of endogenous and exogenous nature. It is abundantly used in the prevention of rickets.
Alpha tocopherol or fat-soluble vitamin E, like ascorbic acid, has strong antioxidant propertiesand participates in the formation of collagen and elastic fibers of connective tissue and skin in particular (supports regenerative capabilitiesorganism to make up for defects). The active component strengthens the walls of the capillaries and improves blood circulation in the vascular bed of small diameter, thus preventing the development of anemia and local blood failure. Provides the normal functioning of plasma and platelet coagulation systems. He is directly involved in education. red blood cells. During pregnancy, alpha tocopherol stimulates the formation of gonadotropinsand regulates development placental tissueso that it meets all the needs of the fetus.
Folic acid is one of the most necessary vitamins for a pregnant woman and when planning an unborn baby. It promotes physiological neuroblast formation and neurocytes embryo, which is important for the normal development of the central and peripheral nervous system. The course of folic acid during pregnancy can prevent the appearance of a large number of hereditary pathologies, for example, neural tube splitting, anencephaly, malformation of the spine and so on. Also this vitamin strengthens the amniotic membrane, thereby preventing possible premature birth. Folic acid is not useless for the mother’s body - it participates in hematopoiesis, as a stimulating factor, thus rendering antianemic effect.
Nicotinamideis active coenzymea wide range of diverse metabolic reactions. So, for example, thanks to its action, fat metabolism is activated and redox processes are normalized. Vitamin A promotes synthesis adrenal hormonesregulating carbohydrate and water-salt metabolism. Takes part in immune responses, providing normal antibody synthesis in response to antigens.
Physiological role calciumlies in the formation of a normal structure bone tissue in the fetus. Due to the exogenous intake of a microelement, a bone germ layer and the rudiments of the future dentin are laid. In combination with vitamin D, it provides active osteomalacia prevention, leaching calcium from the mother and development rickets in a child. Also, the trace element ensures the normal functioning of the cardiovascular system, as it is directly involved in the mechanism of depolarization cardiomyocytesand muscle contraction. Promotes the proper functioning of the blood coagulation system.
Like calcium, phosphorusparticipates in the laying of bone elements and teeth. A distinctive feature is participation in energy exchange - through chemical bonds with nucleotides, macroergic compounds, the so-called molecular energy depots, are formed. If necessary, these structures are destroyed under the influence of a factor of the internal environment and the cell or subcellular organelles receive the necessary amount of energy.
Ironnecessary for synthesis hemeat hemoglobin. It is a protein structure that provides transport of oxygen and carbon dioxide in a red blood cell. Without this microelement, the body would not be able to receive and distribute such vital gas as oxygen to all tissues and organs and remove the waste products in the form of carbon dioxide.
Zincis an active component of various enzymes, protein catalysts of chemical reactions that are predominantly involved in synthesis of glucocorticosteroids, adrenal hormones. Also, its influence extends to the condition of derivatives of the skin - nails and hair.
Manganeseplays an important role in planning pregnancy, as it contributes to activation of reproductive function female body. A trace element also improves memory and reduces irritability, which is beneficial if you take a trace element in the period postpartum depression.
Magnesium, as a biological active component, is included in absolutely all tissues and organs of the human body. It is of the greatest importance in the formation of muscle and bone.
Pharmacodynamics and pharmacokinetics
Elevit Pronatal is complex pharmaceutical preparationcontaining a large number of various active ingredients, the pharmacokinetic abilities of which must be considered separately. However, unfortunately, not all metabolic chains of the active components have been reliably studied.
Vitamin A quickly and fairly completely absorbed from the gastrointestinal tract. The maximum plasma concentration of retinol is reached after 4 hours after taking the drug. He is put off in kupffer cellsfrom where, after reaching a physiological level, it is gradually released into the main bloodstream. Transport Vitamin A in the vascular bed is provided by specific globulinsthat protects the biologically active component from filtering in glomerular apparatus of the kidneys. Retinol is metabolized in tissues with end products of metabolism in the form of carbon dioxide, water-soluble vitamins and fatty acids. In urine, the active component is not detected.
Vitamin C absorbed by their gastrointestinal tract through secondarily active transport along a concentration gradient using sodium ascorbate cotransporterwhich exhibits properties stereospecificity. Further vitamin C enters the mainstream and is transported to cells that metabolize it without residue. Ascorbic acid is found in urine only at excessively higher dosages of the active component.
After oral administration of a pharmaceutical preparation vitamin Dabsorbed from the final sections of the small intestine involving bile acids. In blood, the active component binds to albumin and g-globulins. Cholecalciferol is deposited mainly in adipose tissuesince it is a fat-soluble vitamin in nature. Metabolic transformations occur in:
- skin- under the influence of ultraviolet rays;
- kidney- with the participation parathyroid hormoneproduced by the parathyroid glands, turns into an active metabolite (potent kidney hormone having a steroid structure);
- liver- after the hydroxylation reaction becomes 25-hydroxycholecalciferol.
Most of vitamin D stands out through bile. The elimination half-life makes 19 days.
Thiamineabsorbed in the intestines by active transport in epithelial cellusing a specific carrier. In large quantities, vitamin B1 can also be absorbed by active diffusion. After 15 minutes, it is already detected in blood plasma (the maximum concentration is reached after 1.5 hours), and after only half an hour in various tissues of the body. Deposited vitamin b1 mainly in the brain, kidneys, adrenal glands, liver and heart, since these organs consume thiamine in the largest quantities. The active component of the pharmaceutical product is metabolized due to the liver at an average rate of about 1 mg per day. The elimination half-life ranges from 4 to 6 hours, depending on individual indicators of metabolic rate.
Vitamin B2 absorbed in the gastrointestinal tract by active transport, and then exposed enterohepatic circulation, that is, getting into the vascular bed, passes through the liver. The greatest amount of riboflavin after oral administration is observed in the heart muscle, liver, kidneys and brain. About 10 percent vitamin excretedwith urine, the remaining amount of the active component undergoes a reverse absorption cycle in the tubules of the kidneys, after which it again returns to the main and peripheral bloodstream.
Pyridoxineabsorbed by simple diffusion in the intestine. In blood, it turns into pyridoxamineafter which the final product of exchange is formed 4-pyridoxyl acid without the participation of any biological catalysts. In tissues, vitamin B6 is phosphorylated to organic salts above the indicated acid, which are excreted in the urine. The maximum concentration of vitamin is found in the liver and myocardium, the physiological depot of the active component of the drug Elevit Pronatal.
A little more than half of everything taken is absorbed from the intestines. vitamin e. For its normal absorption, the presence of fatty acids. Tocopherol enters the bloodstream through lymph, binding first to chylomicrons, and in plasma already with beta lipoproteins. Tocopherol accumulates in pituitary gland, testes and adrenal glands. The active component is excreted to a greater extent by bile (approximately ¾ of the entire dosage of the drug), and the remaining amount is excreted in the urine in the form of conjugated glucuronides.
Cyanocobalamin- the only one of the water-soluble vitamins of the Elevit Pronatal complex, which has the property cumulation. This creates an additional risk of overdose of the active component. The cycle of absorption of vitamin B12 is particularly difficult in mind. branched spatial configuration molecules. For its complete absorption, the physiological microflora of the digestive tract, two specific receptors, and certain transmembrane carriers are required.
Indications for use
- insufficiency of minerals and trace elements;
- preventive treatment anemiadue to a deficiency of folic acid, cyanocobalamin or iron;
- correction of mineral metabolism and vitamin metabolism in pregnancy planning;
- period of pregnancyafter childbirth and breastfeeding.
- increased individual sensitivity, hereditary or acquired intolerance to the components of the pharmaceutical preparation;
- hypervitaminosisany of the vitamins;
- high blood calcium;
- impaired kidney or liver function;
- urolithiasis disease;
- nephrolithiasis and urolithiasis;
- increased excretion of calcium in the urine;
- violation of the digestibility and utilization of iron.
As a rule, a pharmaceutical preparation is well tolerated, since the prevailing part of the constituent components of the drug is an element of the physiological metabolism of the human body. However, in clinical practice there are also side effects of a different nature. So, for example, can be observed:
- violation of the functioning of the stomach-intestine system (discomfort in the epigastric region, bloating);
- nausea and vomiting;
- constipation or diarrhea;
- hemolytic anemia with a deficiency of glucose-6-phosphate dehydrogenase;
- headache and dizziness;
- increased irritability;
- allergic reactions - hives, edema, itchy skin or rashes.
Separately, it should be noted possible side effects from the immune system organism, since if they occur, you should immediately seek qualified medical help:
- anaphylactic reactions up to shock with appropriate laboratory and clinical manifestations (extremely rare);
- asthmatic syndrome;
- not cardiogenic pulmonary edema;
- manifestations of the cardiovascular system.
Before conducting a course of conservative treatment, patients should be warned about some consequences of drug therapy that do not have clinical significance:
- perhaps urine staining Intensively yellow due to the large amount vitamin B2;
- feces discolorationin black, due to increased concentration of iron.
Elevit Pronatal, instructions for use (Method and dosage)
The instruction for Elevit Pronatal states that it is extremely simple to use the drug. For the correct administration of a pharmaceutical preparation, no special skills or abilities of medical personnel will be required. Vitamins should be consumed. orally, preferably in the morning, 15 minutes after breakfast. Elevit Pronatal needs to be washed down with a small amount of water.
For pregnant dosage is 1 tablet daily. The course of conservative therapy is determined individually by the attending physician, as a rule, it is prolonged until the end of pregnancy in order to avoid any negative consequences. Therapy can be continued for a while. breastfeeding in the presence of appropriate evidence from the mother.
If, during the course of drug therapy, the instructions for using the drug are clearly followed, the manifestation of symptoms of an overdose is extremely unlikely, since vitamin complexes can persist and be deposited in the body. However, overuse of the drug may develop Vitamin A hypervitaminosis or Daccompanied by such clinical manifestations:
- persistent, difficult to stop constipation;
- strong headache.
There is no specific pharmaceutical antidote for a state of increased concentration of these vitamins. Is used symptomatic therapy each side effect separately.
Vitamins Elevit Pronatal in its composition contains iron, calcium, copper and zinc, the oral administration of which inhibits the absorption capacity antibiotics groups tetracycline and antiviral drugs. With absolute indications for the use of both drugs, it is recommended to make a time interval between doses of drugs in two hours.
Antacid antiulcer pharmaceuticals reduce the absorption of the vitamin complex and trace elements, therefore it is necessary to observe an interval of three hours between the use of the drug.
Use caution with the use of elevit in combination with anticoagulantsor drugs that affect the coagulation system and aggregation platelet count, since development is possible increased coagulation syndrome and increase blood viscositythat is fraught with grave and even fatal consequences. If a course of conservative therapy requires the use of such drugs in combination, regular diagnostic blood tests are recommended.
Treatment laxatives increases the amount of excreted contents from the gastrointestinal tract, which adversely affects the pharmacokinetic ability of Elevit (fewer active ingredients have time to absorb from the surface of the digestive tube, which leads to a decrease in therapeutic effects.
Thiazide diuretics and calcium preparations when combined with a vitamin complex, it increases the risk of hypercalcemia and the deposition of salts of other trace elements in the urinary tract, therefore it is recommended that regular biochemical blood tests be performed to detect the slightest signs of an increased concentration of any fractions.
Concomitant use of Elevit Pronatal with pharmaceuticals such as Levodopa, biophosphonates, fluoroquinolones, Penicillamine, Thyroxine and medications based digitalisreduces their therapeutic effects. However, the mechanism of interaction was not established during clinical trials, therefore, they should be combined with caution in the course of conservative treatment.
The vitamin complex is also able to interact with food. For example, oxalic acid (found in large quantities in spinach and rhubarb) and phytic acid (an integral component of whole grains) inhibit calcium absorption. Therefore, before starting medical treatment, you should additionally consult with a qualified specialist about a diet for the period of conservative therapy.
Terms of sale
Released without presenting the receptor form.
Protect from excessive moisture in a place inaccessible to young children and at a temperature of no higher than 25 degrees Celsius.
Elevit Pronatal does not affect the ability to concentrate and fine motor skills, so driving a car or other complex mechanisms during a course of conservative therapy is not prohibited.
AnalogsMatches for ATX Level 4 code:VitacapGlutamevitBio maxMenopaceLavitaWellmanTheravitGerovitalKaltsinovaPregnakeaOligovitMulti-Tabs IntensiveMulti-Tabs JuniorMulti-Tabs PerinatalMulti-Tabs TeenMulti-Tabs ClassicMulti-Tabs KidDrive outAntioxComplivite Trimesterum
Analogues of the drug Elevit Pronatal constitute a wide group of vitamin complexes that are used in pediatric practice, when planning the conception of a child or directly during gestation.
The most popular are analogues of the drug for pregnant, since this period is accompanied by a deficiency of most vitamin complexes and trace elements. Typically, the following medicines are used: Additive Multivitamins with Minerals, Bio Max, Vitrum, Complies, Multimax.
Vitaftor, Glutamevit, Oligovit, Theravit.
There are no clinically confirmed data on the use of the drug Elevit Pronatal in pediatric practice, but vitamin complexes are actively used to prevent diseases of young children.
The vitamin complex does not interact with the components of alcoholic beverages, however, in order to endure a healthy child, one should give up such bad habits as drinking alcohol and smoking.
Elevit Pronatal for pregnant women (and during lactation)
Vitamins for pregnant women are an extremely important part of the medical prophylaxis of various pathologies and premature births, however, the instructions and the regimen for the use of the pharmaceutical preparation should be clearly followed, since adverse effects are possible.
For example, vitamin A in an amount exceeding 10,000 IU (international units) in the first trimester may have teratogenic properties. Therefore, it is not recommended to independently combine drugs containing a synthetic isomer isotretinoinand etretinateor beta carotene along with a vitamin complex.
Increased quantities may also be harmful. calciferol(in the course of clinical studies, it was proved that excess vitamin D in animals leads to teratogenic effects of the nutrient), since hypercalcemia leads to a delay in the physical and mental development of the fetus, above the valve and aortic stenosisoccurrence retinopathyThe child has.
Separately, it should be said about vitamin D and breastfeeding, since the active component of the drug is able to penetrate into the mother’s milk at excessive concentrations in the body. The highest safe dose for a woman during lactation is 2,000 IU per day. 1 tablet Elevit Pronatal contains 500 IU vitamin D.
Deficiency of vitamins and minerals during childbearing can be avoided if you use Elevit Pronatal with pregnancy planning. In this case, the application regimen becomes not so intense, and the dosage of the drug is reduced so as not to overload the body of the future mother. The beneficial therapeutic effect of this preventive treatment proved in clinical trials, because the physiological depot of useful nutrient components are pre-filled and consumed as needed.
Reviews about Elevit Pronatal
Reviews on Elevit Pronatal at pregnancy planning uninterruptedly reiterate the favorable therapeutic effect of the drug. First of all, doctors note that the fertilization process is much more intensive with a sufficient amount of all fractions of useful nutrients. The development of the fetus is not associated with the risks of various pathologies, as, for example, with a deficiency of vitamins. Trace elements, in turn, are a stimulating factor for the correct laying of vital tissues and organs.
Elevit Pronatal vitamins are also very popular among pregnant women, reviews at various pharmaceutical forums only confirm this fact, because with the current lifestyle, level of inflation and other minor problems it is quite difficult to maintain a healthy diet, and it is very important for a developing child to get all the necessary minerals and vitamins.
Reviews of pregnant women about the pharmaceutical drug Elevit Prenatal were overshadowed only at the very beginning of conservative treatment, since the prevailing category of women faced a deficiency condition directly during the period of gestation. However, insufficiency is easily stopped by drug therapy, which practically does not cause side effects or adverse effects. In addition to the main therapeutic effects on the development of the fetus, the pharmaceutical drug has an effect on the mother's body. Thanks to the active components, normal metabolic pathways are restored, laboratory indicators return to the physiological framework.
Separately, you should take a look at reviews of gynecologists about this drug. Indeed, when planning pregnancy, it is these specialists who monitor the indicators of the female body and the correct course of the period before and after fertilization. Of course, most qualified specialists officially express their approval, since it is much more favorable to proactively eliminate a possible problem than to treat its consequences. The impetus for the development of some hereditary nosological units is the lack of useful nutrients, stopping which in the preventive rehabilitation plan, you can avoid severe pathologies. However, you should not look at a pharmaceutical preparation as a lifesaver; in addition to conservative treatment, a pregnant woman, as she is only planning an unborn child, must necessarily maintain a healthy lifestyle and proper nutrition, abandon bad habits.
Price Elevit Pronatal, where to buy
The price of vitamins in the Russian Federation varies significantly depending on the network of pharmacy stalls. You can buy a complex drug starting from 380 rubles and up to 600 rubles. The price of Elevit Pronatal 100 tablets (pack of 5 blisters for 20 tablets each), of course, is even higher, it is 1230 rubles
The cost of the drug in Ukraine is slightly lower. So the price of Elevit Pronatal for pregnant women is about 120 hryvnia.
Separately, you should find out how much the vitamin complex costs in online pharmacies, as a rule, the price of tablets is much lower, and the delivery of a pharmaceutical product to the door of the house will not take long. Therefore, this option is optimal for the acquisition of Elevit.
- Online Pharmacies in Russia
- Online pharmacies in UkraineUkraine
- Online pharmacies in Kazakhstan
- Elevit pronatal tab. PO n100Rottendorf Pharma GmbH1686 rub.order
- Elevit pronatal tab. PO n30 Rottendorf Pharma GmbH666 rub.order
- Elevit pronatal tablets №30758 rub.order
- Elevit pronatal tablets №1001827 rub.order
Eurofarm * 4% discount on the promotional code medside11
- Elevit pronatal n100 tabletsRottendorf Pharma GmbH / Bayer Kosu2190 rub.order
- Elevit pronatal n30 tabletRottendorf Pharma GmbH 840 rub.order
- Elevit pronatal No. 30 tablets Rottendorf Pharma GmbH, Nimechchina188 UAH.order
- Elevit pronatal N100 tablets Rottendorf Pharma GmbH, Nimechchina571 UAH to order
- Elevit pronatal tablets Elevit Pronatal coated tablets No. 100 Germany, Rottendorf Pharma 616 грн. Order
- Elevit pronatal tablets Elevit Pronatal tablets, coated tablets No. 30 Germany, Rottendorf Pharma 206 UAH order
- Elevit pronatal No. 30 pl.b. Bayer Consumer Care AG, Switzerland, Rottendorf Pharma GmbH GmbH (Germany) 3 tenge to order
- Elevit pronatal No. 100 tablet ppt Bayer Consumer Care AG, Switzerland, Rottendorf Pharma GmbH GmbH (Germany) 7 tenge to order